Exploring the Connection Between GERD and Asthma

If you suffer from asthma and also experience frequent heartburn, you may be surprised to learn that the two could be connected. Gastroesophageal reflux disease (GERD) and asthma are both common, chronic conditions—and research shows they often go hand in hand.

At Tampa Bay Reflux Center, we specialize in diagnosing and treating GERD, with a focus on understanding its far-reaching effects, including its impact on respiratory health. Let's dive into the science behind the GERD-asthma connection and what you can do about it.

What Is GERD?

GERD occurs when stomach acid repeatedly flows back into the esophagus, irritating its lining. Classic symptoms include:

  • Heartburn

  • Regurgitation

  • Chest pain

  • Difficulty swallowing

Less commonly, GERD can cause extra-esophageal symptoms, such as chronic cough, hoarseness, and even asthma flare-ups.

The GERD-Asthma Link: What the Research Says

While it’s not always clear whether GERD causes asthma or vice versa, studies show a strong association between the two:

  • Around 77% of asthma patients experience GERD symptoms, and 82% have abnormal acid exposure in the esophagus (Harding, 2001).

  • Microaspiration of stomach acid or vagal nerve reflexes triggered by acid in the esophagus may lead to bronchoconstriction and worsen asthma (Patterson & Harding, 1999).

  • A narrative review suggests that treating GERD can improve asthma control and quality of life, particularly in patients with poor pulmonary function (Grandes et al., 2022).

  • Despite these connections, studies also highlight that treating asymptomatic GERD doesn’t always improve asthma outcomes, suggesting treatment should be targeted (McCallister et al., 2011).

Symptoms That Overlap

Here are signs that GERD may be affecting your asthma:

  • Asthma symptoms worsen after eating or lying down

  • Frequent coughing, especially at night

  • Poor asthma control despite medication

  • Hoarseness or chronic sore throat

If you notice these signs, a GERD evaluation may be the key to better asthma control.

Diagnosis and Treatment Options

At Tampa Bay Reflux Center, we use advanced diagnostic tools, including:

  • 24-hour esophageal pH monitoring

  • Upper endoscopy

  • Esophageal manometry

Treatment options may include:

  • Proton pump inhibitors (PPIs)

  • Lifestyle modifications (diet changes, weight loss, sleeping position)

  • Surgical options like LINX® Reflux Management System or Nissen fundoplication

By addressing GERD, many patients experience significant relief in asthma symptoms—especially those with nocturnal reflux or poor response to asthma medications.

Why Choose Tampa Bay Reflux Center?

We are Tampa Bay’s premier center for reflux care, offering:

  • Board-certified specialists in GERD and esophageal disorders

  • State-of-the-art diagnostics and minimally invasive treatment

  • Personalized care for patients with complex symptoms like GERD-induced asthma

If you're struggling with both GERD and asthma, you're not alone—and there are solutions.

Works Cited

Grandes, X. A., Manjunatha, R. T., Habib, S., Sangaraju, S. L., & Yepez, D. (2022). Gastroesophageal Reflux Disease and Asthma: A Narrative Review. Cureus, 14. Link

Harding, S. M. (2001). The potential role of gastroesophageal reflux in asthma. Minerva gastroenterologica e dietologica, 47(2), 75–83. Link

Patterson, P., & Harding, S. (1999). Gastroesophageal reflux disorders and asthma. Current Opinion in Pulmonary Medicine, 5(1), 63–67. Link

McCallister, J., Parsons, J. P., & Mastronarde, J. (2011). The relationship between gastroesophageal reflux and asthma: an update. Therapeutic Advances in Respiratory Disease, 5, 143–150. Link